Rui Yi, Ph.D. Principal Investigator
I obtained my B.Sc. at Peking University and my Ph.D. at Duke University. At Duke, I studied RNA nuclear export for cellular and viral mRNAs as well as miRNA precursors in Bryan Cullen's lab. During my postdoc training with Elaine Fuchs at the Rockefeller University, I began to investigate miRNAs and their functions in mammlaian skin. At the University of Colorado, I am leading a group of passionate scientists to decode the fundamental mechanisms in gene expression regulation in mammals.
Dongmei Wang, Ph.D. Research Assistant Professor
I received my Ph.D. in Chinese Academy of Medical Sciences, major in Stem Cell Biology. Before joining the Yi lab in 2009, I worked on bioactive lipids and ovarian cancer in Dr. Yan Xu's lab in Indiana University.
I am interested in using engineered mouse models to study the functions of microRNAs and other important genes in skin development, especially how the cross-talk among different cell types within the epidermis affects each other's development.
Xiying Fan, Ph.D. Postdoctoral Associate, 2011-
I received my Ph.D. at the Institute of Botany, Chinese Academy of Sciences. During Ph.D. training, I studied signal transudction in the light and brassinosteroid pathways at Zhiyong Wang's lab. In the Yi lab, I am investigating miRNA functions in prostate development and prostate cancer.
Alfonso Garrido-Lecca, Ph.D. 2014-
Anna and John J. Sie Foundation Postdoctoral Fellow/NIH T32 Postdoctoral Fellow
I grew up in Lima, Peru and moved to the US when I was 19 years old. I obtained my undergraduate degree in Biology at Texas A&M University. I worked as a technician in the Huang lab at the Texas Children Hospital studying a gene when mutated causes Shwachman-Diamond Syndrome. I did my PhD work in the Blumenthal lab at the University of Colorado studying gene expression and pre-mRNA processing using C. elegans. My current research interest focuses in ncRNAs and regulation of gene expression in Down Syndrome.
Glen Bjerke, Ph.D. Postdoctoral Associate, 2015-
American Cancer Society Postdoctoral Fellow
I obtained my Ph.D. from the University of Virginia in Biochemistry, Molecular Biology and Genetics, where I studied the function of TGF-β signaling in prostate cancer. My current research interest involves elucidating the functions of miRNAs in cancer. To accomplish this we are using new methods to globally identify genes targeted by miRNAs in models of prostate and non-melanoma skin cancer.
Jingjing Wang, Ph.D. Postdoctoral Associate, 2016-
I received my Ph.D. from the Institute of Microbiology, Chinese Academy of Sciences. During my Ph.D. training, I studied the functions of miRNAs in Auxin signaling pathway and plant-virus interaction. At the Yi lab, I am investigating the functions of miRNAs and their targets involved in hair follicle morphogenesis and growth.
Jaimee Hoefert, Graduate Student, 2012-
NIH Ruth L. Kirschstein NRSA Predoctoral Fellow
I received my bachelor's degree from St Olaf College in Minnesota, where I studied biology and Spanish. As an undergraduate, I worked in the lab of Dr Eric Cole characterizing mutant strains of Tetrahymena thermophila, as well as serving as microscopy apprentice. I joined the Yi lab in 2012. I am interested in understanding the role of microRNAs during hair follicle development, and more generally, in understanding how gene networks regulate mammalian developmental processes.
Chi Zhang, Graduate Student, 2017-
I received my Master's degree in Biochemistry and Molecular Biology from Sichuan University, where I focused on unravelling the functions of miRNAs in neural stem cells and during brain development. Now I am interested in studying self-renewal, quiescence and functional exhaustion of tissue stem cells and investigating transcriptional and epigenetic regulation of these important biological processeses.
Jeremy Burgmaier, Lab Manager, 2017-
I earned a Bachelor's degree from the University of Colorado at Boulder in Molecular, Cellular, and Developmental Biology in 2017. As an undergraduate I worked in the Yi lab studying the role of p63 in epidermal fate specification. Now I'm working to uncover the role of p63 in limb and epidermis developmental defects.
Dejiang Feng, Ph.D. (2008-2010)
Jerome Lee, Ph.D. (2012-2016, American Cancer Society Postdoctoral Fellow), Current position: Research Scientist at Archer Genomics.
Zhaojie Zhang, Ph.D., (2009-2013), Previous position: Bioinformatics Research Scientist at St. Jude Children's Research Hospital; Current position: H3 Biomedicine, Boston, MA.
Kent Riemondy, Ph.D., (2009-2015, Postdoctoral associate 2015-2016), Current position: Computional postdoctoral associate with Jay Hesselberth at UC Denver.
Li Wang, Ph.D., (2010-2015), Insight Health Data Science fellow. Current position: Computational biologist at the Broad Institute, Boston MA.
Christopher Bennett, Ph.D. (2012-2016), Current position: Membrane Protective Technologies, Fort Collins, CO.
Sarah Jackson, Honors Student, Summa Cum Laude (2009-2011).
Emily Shangraw, Honors Student, Summa Cum Laude (2009-2011).
Sarah Ha, Honors Student, Summa Cum Laude (2010-2013), Current position: MD student at University of Colorado School of Medicine
Meaghan Flagg, Honors Student, Summa Cum Laude (2010-2013), Current position: Graduate student at Harvard Medical School
Lara Janiszewski, Honors Student, Summa Cum Laude (2014-2015), Current position: Graduate student at CU Boulder
Valerie Gao (2014-2015)
Ziqi Liu (2014-2016)
Rachel Hall (2015-2016)
Chloe Yan (2015-2016)
Jeremy Burgmaier, Honors Student, Summa Cum Laude (2016-2017), Current position: Lab manager of the Yi lab
Evan O'Loughlin (2008-2011), Current position: Graduate student at Harvard Medical School
Loren Greiner (2009-2013), retired
Emily Beans (2011-2014), Current position: MD student at Indiana University School of Medicine
Andrew Fink (2014), Current position: Master student at Stanford University Environmental Engineering & Science
Lisa Kormendi (2014-2017), Current position: MD student at University of Colorado School of Medicine
High School Students:
Larry Zhang (2011-2013), Current position: MIT undergraduate