Publications:

Science Cover NCB Cover

2008-current

27. Yi R (2017) Mechanisms of Quiescent Hair Follicle Stem Cell Regulation. Stem Cells Link (Review)

26. Latil M, Nassar D, Beck B, Boumahdi S, Wang L, Brisebarre A, Dubois C, Nkusi E, Lenglez S, Checinska A, Vercauteren Drubbel A, Devos M, Declercq W, Yi R, Blanpain C (2016) Cell-type-specific chromatin states differentially prime squamous cell carcinoma tumor-initiating cells for epithelial to mesenchymal transition. Cell Stem Cell Link (collaboration)

25. Rezza A, Wang Z, Sennett R, Qiao W, Wang D, Heitman N, Mok KW, Clavel C, Yi R, Zandstra P, Ma'ayan A, Rendl M (2016) Signaling networks among stem cell precursors, transit-amplifying progenitors, and their niche in developing hair follicles. Cell Reports Link (collaboration)

24. Bennett CG*, Riemondy K*, Chapnick DA, Bunker E, Liu X, Kuersten S and Yi R (2016) Genome-wide analysis of Musashi-2 targets reveals novel functions in governing epithelial cell migration. Nucleic Acids Research Link. *Co-first authors.

23. Wang L, Siegenthaler JA, Dowell RD and Yi R (2016) Foxc1 reinforces quiescence in self-renewing hair follicle stem cells. Science 351: 613-617. Link PDF Link HTML Link (Cover article)

22. Riemondy K, Wang XJ, Torchia EC, Roop DR and Yi R(2015) MicroRNA-203 represses selection and expansion of oncogenic HRas transformed tumor initiating cells. eLife 2015; 10.7554/eLife.07004. Link

21. Riemondy K, Hoefert JE and Yi R(2014). Not miR-ly micromanagers: the functions and regulatory networks of miRNAs in mammalian skin. Wiley Interdiscip Rev RNA. 5: 849-865. Link

20. Lee JE and Yi R (2014). Highly efficient ligation of small RNA molecules for microRNA quantitation by high-throughput sequencing. Journal of Visualized Experiments. 93: e52095. Link

19. White AC, Khuu JK, Dang CY, Hu J, Tran KV, Liu A, Gomez S, Zhang Z, Yi R, Scumpia P, Grigorian M, Lowry WE (2014). Stem cell quiescence acts as a tumor suppressor in squamous tumours. Nature Cell Biology 16: 99-107. Link (collaboration)

18. Wang L and Yi R (2014). 3’UTRs take a long short in the brain. Bioessays. 36: 39-45. Link

17. Zhang Z*, Lee JE*, Riemondy K, Anderson EM and Yi R (2013). High-efficiency RNA cloning enables accurate quantification of miRNA expression by deep sequencing. Genome Biology 14: R109. *Co-first authors. Link

16. Wang D, Zhang Z, O’Loughlin E, Wang L, Fan X, Lai EC and Yi R (2013). MicroRNA-205 controls neonatal expansion of skin stem cells by modulating the PI(3)K pathway. Nature Cell Biology 15: 1153-1163. Link (Cover Article)

15. Jackson SJ*, Zhang Z*, Feng D, Flagg M, O’Loughlin E, Wang D, Stokes N, Fuchs E and Yi R (2013). Rapid and widespread suppression of self-renewal by microRNA-203 during epidermal differentiation. Development140:1882-1891. Link.*Co-first authors.

14. Wang L, Dowell RD and Yi R (2013). Genome-wide maps of polyadenylation reveal dynamic mRNA 3’end formation in mammalian cell lineages. RNA  19: 413-425. Link

13. Wang D, Zhang Z, O’Loughlin E, Lee T, Houel S, O’Carroll D, Tarakhovsky A, Ahn NG, and Yi R (2012). Quantitative functions of Argonaute proteins in mammalian development. Genes & Development 26: 693-704. Link

12. Yi R* and Fuchs E* (2012). A miR image of stem cells and their lineages. Curr Top Dev Biol 99: 175-199. *Co-corresponding author, invited review. Link

11. Yi R* and Fuchs E* (2011). MicroRNAs and their roles in mammalian stem cells. Journal of Cell Science 124: 1775-1783.  *Co-corresponding author, invited review. Link

10. Yi R* and Fuchs E* (2010). MicroRNA-mediated control in the skin. Cell Death & Differentiation 17: 229-235. *Co-corresponding author, invited review. Link

2004-2008

9. Yi R, Pasolli HA, Landthaler M, Hafner M, Ojo T, Sheridan R, Sander C, O'Carroll D, Stoffel M, Tuschl T and Fuchs E (2009). DGCR8-dependent microRNA biogenesis is essential for skin development. PNAS 106: 498-502. Link

8. Yi R, Poy MN, Stoffel M and Fuchs E (2008). A skin microRNA promotes differentiation by repressing ‘stemness’.  Nature 452: 225-229. Link

7. Yi R, O’Carroll D, Pasolli HA, Zhang Z, Dietrich FS, Tarakhovsky A and Fuchs E (2006). Morphogenesis in skin is governed by discrete sets of differentially expressed microRNAs. Nature Genetics 38: 356-362. Link

1999-2004

    6. Yi R, Doehle BP, Qin Y, Macara IG and Cullen BR (2005). Overexpression of Exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs. RNA 11: 220–226. Link

    5. Zeng Y, Yi R and Cullen BR (2005). Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha. The EMBO J. 24: 138–148. Link

    4. Yi R, Qin Y, Macara IG and Cullen BR (2003). Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs. Genes & Development 17: 3011-3016. Link

      3. Zeng Y, Yi R and Cullen BR. (2003). MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms. PNAS 100: 9779-9784. Link

      2. Yi R, Bogerd HP and Cullen BR. (2002). Recruitment of the Crm1 nuclear export factor is sufficient to induce cytoplasmic expression of incompletely spliced human immunodeficiency virus mRNAs. Journal of Virology 76: 2036-2042. Link

    1. Yi R, Bogerd HP, Wiegand HL and Cullen BR. (2002). Both Ran and Importins have the ability to function as nuclear mRNA export factors. RNA 8: 180-187. Link